前辅文
Preface
Chapter 1. The HIV Pandemic
1.1. Introduction
1.2. Prototype Dynamics
1.3. Effect of Drug Treatment
1.4. Other Players in the Immune System
1.5. Time Delay
1.6. Conclusion
Chapter 2. Basic Facts of Immunology
2.1. Introduction
2.2. Lymphocytes
2.3. MHC Interactions
2.4. Receptors
2.5. Learning and Memory
2.6. The Self/Nonself Discrimination Problem
Chapter 3. Quantifying the Immune Response (Assays)
3.1. Rosette Formation
3.2. Limiting Dilution Analysis
3.3. RIA and ELISA
3.4. Hemolytic Plaque Technique
Chapter 4. Modeling Humoral Immune Responses
4.1. Binding Process
4.2. Multivalent Binding
4.3. Network Formation
4.4. B-Cell Progression
4.5. Evolutionary Training of Ag-Ab Complementarity
4.6. Affinity Maturation
4.7. Hypermutation Sequence
4.8. Humoral Response at Low Resolution
Chapter 5. Modeling Cell-Mediated Response
5.1. Cell-Mediated Toxicity
5.2. Immune Surveillance
5.3. Effect of Fluctuations
5.4. Tumor Escape
Chapter 6. Control of Immune Response
6.1. Immune Networks
6.2. Estimates of Connectivity
6.3. Cytokine Networks
Chapter 7. Viewpoint of the Virus
7.1. Reprise
7.2. Short-Time Strategy
7.3. Intermediate Time Control
General References
Index
